Simparica Trio For Dogs
Simparica Trio is a once-monthly, tasty chew that delivers broad-spectrum protection in a single, easy dose. This triple-action formula helps shield dogs from the inside out—preventing heartworm disease while treating and controlling fleas, ticks, roundworms, and hookworms.
The fast-acting, palatable chew makes dosing simple and stress-free for pets and their people. It’s also the only monthly product proven to kill six species of ticks, including the deer tick, a common carrier of Lyme disease.
Safe for puppies as young as 8 weeks and weighing at least 2.8 lb, Simparica Trio is a reliable choice for early and ongoing parasite prevention.
Parasites Prevention
Fleas
Ticks
Heartworm
Intestinal worms
Fleas don’t wait. Within five minutes they’re biting and may transmit pathogens. Those bites can escalate from a mild itch to raw skin and patchy hair loss. One adult can spark an outbreak—laying up to 1,300 eggs in just 50 days. Break the cycle with Simparica Trio: it begins eliminating fleas within 4 hours and reaches peak effect by 8, stopping egg-laying before it starts.
Ticks don’t take a season off—they’re active across every U.S. region all year, so protection can’t be seasonal. They also carry and spread at least 15 serious diseases in dogs, including Lyme disease, ehrlichiosis, and anaplasmosis. Simparica Trio delivers strong tick defense, killing six tick species—including the deer tick—and helping block the transmission of tick-borne infections.
One infected mosquito is all it takes to transmit heartworm larvae—putting your dog at risk of a potentially fatal disease. Heartworm has been confirmed in all 50 states, so exposure is everywhere. Because infection may not show up on routine tests for up to nine months, it can progress silently between screenings. Left untreated, heartworm can cause severe lung damage, lead to heart failure, and be deadly.
Intestinal worms don’t just steal nutrients—they inflame and damage the gut, which can lead to lasting digestive issues. Infected dogs may develop a pot-bellied appearance, vomiting, diarrhea, and dehydration, with young or immunocompromised pets hit hardest. Because roundworms and hookworms shed eggs in feces, infected dogs can contaminate yards, parks, and living spaces—putting other pets and even people at risk. Puppies face the greatest danger, often acquiring parasites before birth or through nursing, so early, consistent deworming is essential.